Celebrating 10 Years | 2019

The Society for Neuroscience launched its gold open-access journal in November 2014. As founding Editor-in-Chief Christophe Bernard said in his editorial, “eNeuro at Ten: Just Warming Up,” “eNeuro was designed to serve the community of neuroscientists.”

To celebrate 10 years of eNeuro, throughout the year the blog will highlight findings of some of the most-cited papers published in each year of the journal’s history.

2019

“Females Are Not Just ‘Protected’ Males”: Sex-Specific Vulnerabilities in Placenta and Brain after Prenatal Immune Disruption
Amy E. Braun, Pamela A. Carpentier, Brooke A. Babineau, Aditi R. Narayan, Michelle L. Kielhold, Hyang Mi Moon, Archana Shankar, Jennifer Su, Vidya Saravanapandian, Ursula Haditsch, and Theo D. Palmer

Maternal immune activation during pregnancy had not been investigated in female offspring prior to this study, positing it as a critical advancement for the field. Braun et al. assessed the impact of lipopolysaccharide-induced inflammation during pregnancy on female fetuses and offspring. They found that this manipulation has significantly different effects on females than males.

 

Effects of Single Cage Housing on Stress, Cognitive, and Seizure Parameters in the Rat and Mouse Pilocarpine Models of Epilepsy
H. Manouze, A. Ghestem, V. Poillerat, M. Bennis, S. Ba-M’hamed, J. J. Benoliel, C. Becker, and C. Bernard

Single animal housing is commonly used during experiments across many subfields of neuroscience. Prior to this publication, it was suspected that housing animals in individual cages induces more severe pathological outcomes for them. But Manouze and colleagues were the first to directly test this. They found that singly housed rats and mice develop a more severe phenotype of stress and epilepsy as group housed animals.