Disorders of the Nervous System
This image shows coronal slices at the level of the hippocampus in TRAP2 mice labeling neuronal ensembles during a rewarded T-maze spatial memory task.
This paper presents an elegant study examining neuronal activation in multiple brain regions involved in learning and consolidation of an alternation task.
This image shows the demyelinating optic nerve of a mouse model with impaired visual function.
The midline topographical organization of the corpus callosum of a newborn mouse.
Striatal Neurons of a Parkinson’s disease model
An image of cortical neurons in the mouse model of Alzheimer’s disease.
Authors highlight a deficit in motor skill consolidation-dependent synaptic plasticity at motor cortex to dorsal striatum synapses that represents an early biomarker for Huntington’s Disease in mice.
Reginald Cannady and Sudarat Nimitvilai-Roberts tell the story about their co-first author paper about time-dependent changes in cellular excitability of neurons in the prefrontal cortex following chronic voluntary ethanol drinking in mice.
Authors demonstrate that epidermal growth factor receptor antagonism not only blocks morphine tolerance but also restores the effectiveness of opioids against neuropathic pain.
An image of blood vessels in a region of the parietal cortex of a mouse with laminin, pericytes, and cell nuclei visible.