Disorders of the Nervous System
Dr. Paul Baudin, currently completing his medical degree at the Sorbonne Paris Nord university, tells us how his Ph.D. broadened his conceptualization of neurological diseases and treatments, and emphasizes the importance of publishing negative data.
The authors explain how splicing variation (3R vs. 4R) and cytoplasmic tethering (by 14-3-3) blunt the pathogenicity of phosphorylated tau during normal brain development.
This image shows coronal slices at the level of the hippocampus in TRAP2 mice labeling neuronal ensembles during a rewarded T-maze spatial memory task.
This paper presents an elegant study examining neuronal activation in multiple brain regions involved in learning and consolidation of an alternation task.
This image shows the demyelinating optic nerve of a mouse model with impaired visual function.
The midline topographical organization of the corpus callosum of a newborn mouse.
Striatal Neurons of a Parkinson’s disease model
An image of cortical neurons in the mouse model of Alzheimer’s disease.
Authors highlight a deficit in motor skill consolidation-dependent synaptic plasticity at motor cortex to dorsal striatum synapses that represents an early biomarker for Huntington’s Disease in mice.
Reginald Cannady and Sudarat Nimitvilai-Roberts tell the story about their co-first author paper about time-dependent changes in cellular excitability of neurons in the prefrontal cortex following chronic voluntary ethanol drinking in mice.
- Reviewer Spotlight: Dr. Feng Feng
- Snapshots in Neuroscience: Developing Vagal Sensory Cell Types
- Editor’s Pick: The importance of thorough genetic investigation of transgenic models
- Editor's Pick | It pays to be young: why fetal tau phosphorylation differs from that found in Alzheimer's Disease
- Reviewer Spotlight: Dr. Aditya Singh