Neuroscience Research

Authors show interneuron defects in a new mouse model of premature birth that combines prenatal inflammatory and postnatal hypoxic insults.
By Sarah Santiago, PhD
August 15, 2019

Authors show interneuron defects in a new mouse model of premature birth that combines prenatal inflammatory and postnatal hypoxic insults.

Authors show that although handedness impacts the accuracy of hand movement control, it has virtually no influence on the ability to predict the visual consequences of hand movements.
By Rosalind S.E. Carney, DPhil
August 8, 2019

Authors show that although handedness impacts the accuracy of hand movement control, it has virtually no influence on the ability to predict the visual consequences of hand movements.

Emanuela De Falco, PhD, Postdoctoral Fellow, Indiana University-Purdue University Indianapolis [IUPUI], Indianapolis, IN.
By Rosalind S.E. Carney, DPhil
July 25, 2019

Dr. Emanuela De Falco tells the story about her co-first author eNeuro paper that describes distinct neural activity states that occur in the medial prefrontal cortex while rats perform an odor span task of working memory capacity.

By Pablo S. Villar
July 18, 2019

Authors show that one olfactory cortical structure, the olfactory tubercle, is unique among olfactory cortices in that it lacks feedback projections to the olfactory bulb.

See the most shared articles of May/June 2019; Volume 6,Issue 3
By SfN Staff
July 11, 2019

See the most shared articles of May/June 2019; Volume 6,Issue 3

Authors show that blocking endogenous Bone Morphogenetic Protein 4 signaling via a selective pharmacological approach promotes oligodendroglial differentiation and increases the rate of remyelination after a central demyelinating insult in vivo.
By Claudia Lopez-Lloreda
June 27, 2019

Authors show that blocking endogenous Bone Morphogenetic Protein 4 signaling via a selective pharmacological approach promotes oligodendroglial differentiation and increases the rate of remyelination after a central demyelinating insult in vivo.

Authors tested whether native English-speaking adults could learn a second, visually atypical writing system, HouseFont, and used neuroimaging data to assess the location of any learning effects.
By Rosalind S.E. Carney, DPhil
June 20, 2019

Authors tested whether native English-speaking adults could learn a second, visually atypical writing system, HouseFont, and used neuroimaging data to assess the location of any learning effects.

Authors provide the first functional description of the emergence of neocortical fast ripples in hippocampal epilepsy and show that cross-frequency coupling might be a fundamental mechanism underlying the spreading of epileptic activity.
By William Stacey, MD, PhD
June 13, 2019

Authors provide the first functional description of the emergence of neocortical fast ripples in hippocampal epilepsy and show that cross-frequency coupling might be a fundamental mechanism underlying the spreading of epileptic activity.

Associate Professor, Ricardo Araneda, PhD, Department of Biology, University of Maryland, College Park, MD, and PhD Candidate, Ruilong Hu, Neuroscience & Cognitive Sciences Program, University of Maryland, College Park, MD.
By Rosalind S.E. Carney, DPhil
June 6, 2019

PhD Candidate Ruilong Hu and Dr. Ricardo Araneda tell the story about their eNeuro publication that showed that the two predominant subtypes of inhibitory neurons in the main olfactory bulb, the granule cells and periglomerular cells, exhibit subthreshold resonance mediated by hyperpolarization-activated currents (Ih), as opposed to the primary output neurons, the mitral cells.

Figure 1. High-speed confocal imaging and LFP recording in the forebrain of GCaMP-expressing zebrafish larvae. (A) Timeline of confocal imaging and LFP recording relative to immobilization of larvae in agar and exposure to convulsant drugs. High-speed confocal recordings were obtained ∼40 minutes after drug exposure, with 5× and 20× objectives used for whole-brain and single neuron imaging, respectively. (B) Simultaneous high-speed confocal imaging and LFP recording in agar-embedded larvae. (C) Schematic illustration depicting sub-regions of the larval zebrafish brain. (D) Representative 5× image of Tg(neurod1:GCaMP6f) zebrafish at 5–6 days postfertilization. (Adapted from Figure 1 in Liu & Baraban et al., 2019.)
By Rosalind S.E. Carney, DPhil
May 9, 2019

Authors used well-established seizure protocols and fast confocal imaging of genetically encoded calcium indicator-expressing zebrafish to investigate epileptic network properties at brain-wide and single-cell levels.