These partial 3D reconstructions of synapses from wild-type and synapsin knock-out mice show the presynaptic membrane, the postsynaptic membrane, and synaptic vesicles.

Looking back at ten years of eNeuro papers, this post features two papers published in 2018.

Slice culture study reveals that prolonged silencing of neurons induces context-specific seizure-like activity that is only partially reversible and explores the underlying mechanism.

Removing inhibition in the hippocampus increases epileptic seizures, but not as severely or as long-lasting as neuroscientists may predict.

Looking back at ten years of eNeuro papers, this post features two papers published in 2016.

Researchers find that synaptotagmin-7 plays an important role in dopamine release during phasic bursts of firing.

Confocal image of the hippocampus showing somatostatin inhibitory neurons (green).

This study reveals consequences of SYNGAP1 haploinsufficiency in hippocampal GABAergic interneurons.

These images show the GABAA receptor δ subunit expressed on parvalbumin-positive interneurons in the basolateral amygdala.

Authors highlight TrkB-dependent molecular pathways as critical for the maturation of inhibitory interneurons and support the hypothesis that loss of BDNF signaling in cortistatin interneurons leads to altered excitatory/inhibitory balance.