Reader's Pick

An automated analysis approach to reduce the heterogeneity of dendritic spine morphology could enhance reproducibility in neurological disorders with defective synaptic transmission.
By Juan C Sanchez-Arias, MD, and Simona D Frederiksen, PhD
December 5, 2019

An automated analysis approach to reduce the heterogeneity of dendritic spine morphology could enhance reproducibility in neurological disorders with defective synaptic transmission.

Authors targeted the microglia-specific Tmem119 gene to generate two novel mouse models that can be used to visualize and control reporter protein expression in microglia with improved distinction from closely related cell types
By Dah-eun (Chloe) Chung, PhD
October 31, 2019

Authors targeted the microglia-specific Tmem119 gene to generate two novel mouse models that can be used to visualize and control reporter protein expression in microglia with improved distinction from closely related cell types.

Authors suggest that blue light stimulation is ill-suited to long-term optogenetic experiments, especially those that measure transcription.
By Thiago Arzua
October 23, 2019

Authors suggest that blue light stimulation is ill-suited to long-term optogenetic experiments, especially those that measure transcription.

This research offers an important contribution to the knowledge of molecular mechanism of worm learning and sensory integration that may be applicable to learning in many organisms.
By Kaitlin H. Snider, PhD
October 3, 2019

This research offers an important contribution to the knowledge of molecular mechanism of worm learning and sensory integration that may be applicable to learning in many organisms.

Authors show that key features of the microglial activation pattern observed after status epilepticus may not be related to the epileptogenic process.
By Atehsa Sahagun
September 5, 2019

Authors show that key features of the microglial activation pattern observed after status epilepticus may not be related to the epileptogenic process.

Authors show interneuron defects in a new mouse model of premature birth that combines prenatal inflammatory and postnatal hypoxic insults.
By Sarah Santiago, PhD
August 15, 2019

Authors show interneuron defects in a new mouse model of premature birth that combines prenatal inflammatory and postnatal hypoxic insults.

By Pablo S. Villar
July 18, 2019

Authors show that one olfactory cortical structure, the olfactory tubercle, is unique among olfactory cortices in that it lacks feedback projections to the olfactory bulb.

Authors show that blocking endogenous Bone Morphogenetic Protein 4 signaling via a selective pharmacological approach promotes oligodendroglial differentiation and increases the rate of remyelination after a central demyelinating insult in vivo.
By Claudia Lopez-Lloreda
June 27, 2019

Authors show that blocking endogenous Bone Morphogenetic Protein 4 signaling via a selective pharmacological approach promotes oligodendroglial differentiation and increases the rate of remyelination after a central demyelinating insult in vivo.

Authors show that the same stress can elicit divergent morphological effects in astrocytes in the hippocampus versus the amygdala.
By Abha Karki Rajbhandari, PhD
March 28, 2019

Authors show that the same stress can elicit divergent morphological effects in astrocytes in the hippocampus versus the amygdala.

Authors show that the memory of eating a recent meal likely inhibits subsequent food consumption.
By Benjamin M. Seitz
March 21, 2019

Authors show that the memory of eating a recent meal likely inhibits subsequent food consumption.