Neuronal Excitability

line drawing of brain inside side view of head with blue background
By SfN Staff
June 13, 2024

Slice culture study reveals that prolonged silencing of neurons induces context-specific seizure-like activity that is only partially reversible and explores the underlying mechanism.

line drawing of brain inside side view of head with green background
By SfN Staff
May 23, 2024

Removing inhibition in the hippocampus increases epileptic seizures, but not as severely or as long-lasting as neuroscientists may predict.

By SfN Staff
May 2, 2024

Looking back at ten years of eNeuro papers, this post features two papers published in 2016.

line drawing of brain inside side view of head with blue background
By SfN Staff
February 22, 2024

Researchers find that synaptotagmin-7 plays an important role in dopamine release during phasic bursts of firing.

By SfN Staff
December 14, 2023

Confocal image of the hippocampus showing somatostatin inhibitory neurons (green).

line drawing of brain inside side view of head with red background
By SfN Staff
May 18, 2023

This study reveals consequences of SYNGAP1 haploinsufficiency in hippocampal GABAergic interneurons.

By SfN Staff
August 18, 2022

These images show the GABAA receptor δ subunit expressed on parvalbumin-positive interneurons in the basolateral amygdala.

Image of brain
By Catherine Smoot
August 20, 2020

Authors highlight TrkB-dependent molecular pathways as critical for the maturation of inhibitory interneurons and support the hypothesis that loss of BDNF signaling in cortistatin interneurons leads to altered excitatory/inhibitory balance.

Image of electron micrographs of untreated, control lamprey synapses stimulated at 20 Hz for 5 min.
By Rosalind S.E. Carney, DPhil
July 9, 2020

Authors report a viable chaperone-based strategy for reversing the synaptic vesicle trafficking defects associated with excess α-synuclein, which may be of value for improving synaptic function in Parkinson’s disease and other synucleinopathies.

Synaptic boutons in the muscle of a larval fruit fly
By SfN Staff
March 26, 2020

Synaptic boutons in the muscle of a larval fruit fly