Featured Findings

Figure 1. Leeches that recover crawling behavior have established regrowth of afferent input to the lead ganglion. (A) In leeches that recover crawling behavior after injury, Neurobiotin labels fibers in the M3 nerve, which project into the M3 ganglion. (B) In leeches that do not recover crawling behavior after injury, Neurobiotin-labeled fibers are not observed in the M3 ganglion. (Figure 8 in Puhl et al. 2018.)
By Rosalind S.E. Carney, DPhil
December 13, 2018

Authors demonstrate that in the absence of descending cephalic input, locomotor recovery in the leech is achieved by a switch to dependence on afferent information from peripheral nerves in the body wall.

By Rosalind S.E. Carney, DPhil
October 31, 2018

Authors demonstrate that capsaicin, a TRPV1 agonist, activates a pro-axon growth program, suggesting an approach for enhancing axon regeneration in selective populations of neurons.

Mitochondrial Ultrastructure is Optimized for Synaptic Performance (Adapted from Figure 3 in Cserép et al., 2018)
By Rosalind S.E. Carney, DPhil
September 21, 2018

Authors find an evolutionarily conserved, cell-type independent coupling of mitochondrial ultrastructure to synaptic performance.