Disorders of the Nervous System
Authors used well-established seizure protocols and fast confocal imaging of genetically encoded calcium indicator-expressing zebrafish to investigate epileptic network properties at brain-wide and single-cell levels.
Authors show that the same stress can elicit divergent morphological effects in astrocytes in the hippocampus versus the amygdala.
Authors found that experimentally induced stroke causes a secondary wave of brain tissue inflammation that shares some molecular and morphological characteristics with atherosclerosis.
Authors demonstrate that capsaicin, a TRPV1 agonist, activates a pro-axon growth program, suggesting an approach for enhancing axon regeneration in selective populations of neurons.
Authors functionally defined immediate-early astrocytes (ieAstrocytes) as an in vivo astrocyte population, modulated by S1P signaling, in a mouse model of multiple sclerosis.
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