Development

Purkinje cell clusters in the mouse cerebellum at embryonic day 17.5
By SfN Staff
January 21, 2021

Purkinje cell clusters in the mouse cerebellum at embryonic day 17.5.

an interneuron migrating on a monolayer of cortical feeder cells in an in vitro co-culture assay
By SfN Staff
November 5, 2020

This image shows an interneuron migrating on a monolayer of cortical feeder cells in an in vitro co-culture assay.

an immunostained whole-mount preparation of a mouse cochlea
By SfN Staff
October 8, 2020

This image shows an immunostained whole-mount preparation of a mouse cochlea.

MAP2+ (magenta) neurites from cultured immature cortical neurons extending into a stripe of chondroitin sulfate proteoglycans (CSPGs; green) treated with chondroitinase ABC (chABC), an enzyme that abolishes CSPGs
By SfN Staff
September 24, 2020

This image shows MAP2+ neurites from cultured immature cortical neurons extending into a stripe of chondroitin sulfate proteoglycans (CSPGs) treated with chondroitinase ABC, an enzyme that abolishes CSPGs

Spiking patterns of MeA Dbx1- and Foxp2-lineage neurons differ across sex and lineage.
By Rosalind S.E. Carney, DPhil
August 13, 2020

Authors show neuronal subpopulation and sex differences in the biophysical signatures of developmentally defined medial amygdala output neurons.

Image of brain
By Nicole Amberg and Robert Beattie
June 18, 2020

Authors examined the reliability of using Cre-induced recombination of one gene to predict recombination in another gene at the single-cell level in adult hippocampal neural stem and progenitor cells.

Drs. Alexandra Castillo-Ruiz and Nancy Forger sitting in their lab.
By Rosalind S.E. Carney, DPhil
June 11, 2020

Alexandra Castillo-Ruiz and Nancy Forger tell the story about their eNeuro paper that sheds light on the long-standing question of what controls the timing and magnitude of developmental neuronal cell death.

Authors demonstrate that ApoE deficiency and the ApoE4 human isoform both impair hippocampal neurogenesis in adult mice and give insight into how ApoE may influence hippocampal-related neurological diseases.
By David Graykowski
April 9, 2020

Authors demonstrate that ApoE deficiency and the ApoE4 human isoform both impair hippocampal neurogenesis in adult mice and give insight into how ApoE may influence hippocampal-related neurological diseases.

Authors describe the in vivo behavior of mitochondria at the growth cone of elongating retinal axons in zebrafish.
By Rosalind S.E. Carney, DPhil
February 6, 2020

Authors describe the in vivo behavior of mitochondria at the growth cone of elongating retinal axons in zebrafish.

Authors show interneuron defects in a new mouse model of premature birth that combines prenatal inflammatory and postnatal hypoxic insults.
By Sarah Santiago, PhD
August 15, 2019

Authors show interneuron defects in a new mouse model of premature birth that combines prenatal inflammatory and postnatal hypoxic insults.