Reader's Pick

Image of brain
By Nicole Amberg and Robert Beattie
June 18, 2020

Authors examined the reliability of using Cre-induced recombination of one gene to predict recombination in another gene at the single-cell level in adult hippocampal neural stem and progenitor cells.

By Mariella Bodemeier Loayza Careaga, PhD
May 14, 2020

Authors explored the role of the Bed Nucleus of the Stria Terminalis in the reinstatement and renewal of fear—two forms of fear relapse that are differentially triggered by stress.

By Shelby White
April 23, 2020

Chronic ethanol exposure and withdrawal in rats produce opposing effects on glutamate release in the basolateral amygdala from axons originating in subdivisions of the medial prefrontal cortex, chemogenetic inhibition attenuates the increase in anxiety-like behavior associated with ethanol withdrawal.

Authors demonstrate that ApoE deficiency and the ApoE4 human isoform both impair hippocampal neurogenesis in adult mice and give insight into how ApoE may influence hippocampal-related neurological diseases.
By David Graykowski
April 9, 2020

Authors demonstrate that ApoE deficiency and the ApoE4 human isoform both impair hippocampal neurogenesis in adult mice and give insight into how ApoE may influence hippocampal-related neurological diseases.

Authors demonstrate that long-distance axon regeneration can drive recovery of respiratory function following cervical spinal cord injury in rats.
By Lydia E. Strattan
February 27, 2020

Authors demonstrate that long-distance axon regeneration can drive recovery of respiratory function following cervical spinal cord injury in rats.

An automated analysis approach to reduce the heterogeneity of dendritic spine morphology could enhance reproducibility in neurological disorders with defective synaptic transmission.
By Juan C Sanchez-Arias, MD, and Simona D Frederiksen, PhD
December 5, 2019

An automated analysis approach to reduce the heterogeneity of dendritic spine morphology could enhance reproducibility in neurological disorders with defective synaptic transmission.

Authors targeted the microglia-specific Tmem119 gene to generate two novel mouse models that can be used to visualize and control reporter protein expression in microglia with improved distinction from closely related cell types
By Dah-eun (Chloe) Chung, PhD
October 31, 2019

Authors targeted the microglia-specific Tmem119 gene to generate two novel mouse models that can be used to visualize and control reporter protein expression in microglia with improved distinction from closely related cell types.

Authors suggest that blue light stimulation is ill-suited to long-term optogenetic experiments, especially those that measure transcription.
By Thiago Arzua
October 23, 2019

Authors suggest that blue light stimulation is ill-suited to long-term optogenetic experiments, especially those that measure transcription.

This research offers an important contribution to the knowledge of molecular mechanism of worm learning and sensory integration that may be applicable to learning in many organisms.
By Kaitlin H. Snider, PhD
October 3, 2019

This research offers an important contribution to the knowledge of molecular mechanism of worm learning and sensory integration that may be applicable to learning in many organisms.

Authors show that key features of the microglial activation pattern observed after status epilepticus may not be related to the epileptogenic process.
By Atehsa Sahagun
September 5, 2019

Authors show that key features of the microglial activation pattern observed after status epilepticus may not be related to the epileptogenic process.