Authors highlight TrkB-dependent molecular pathways as critical for the maturation of inhibitory interneurons and support the hypothesis that loss of BDNF signaling in cortistatin interneurons leads to altered excitatory/inhibitory balance.
Sex- and Genetic Lineage-dependent Variations in the Electrophysiological Properties of Medial Amygdala Neurons
Authors show neuronal subpopulation and sex differences in the biophysical signatures of developmentally defined medial amygdala output neurons.
Tonebox: Automated Tool for Behavioral Analyses and Potential Integration With Other Open Source Methods
Authors developed the open-source ToneBox tool, which allows both novice and expert behaviorists to automatically test hundreds of mice simultaneously on different behavioral tasks.
Parley Belsey and Eric Yttri tell the story about how they created a highly customizable, low cost and reproducible open-source behavior training platform for studying motor control, decision-making, and reaching reaction time in rodents.
Neurons responding to medicinal and abused opioids are visualized for the first time in the mouse brain.
See the most-shared articles of May/June 2020; Volume 7, Issue 3
Authors report a viable chaperone-based strategy for reversing the synaptic vesicle trafficking defects associated with excess α-synuclein, which may be of value for improving synaptic function in Parkinson’s disease and other synucleinopathies.
Heterogeneity of neuronal cell bodies of sensory nerves within the vagal ganglia.
Authors examined the reliability of using Cre-induced recombination of one gene to predict recombination in another gene at the single-cell level in adult hippocampal neural stem and progenitor cells.
Alexandra Castillo-Ruiz and Nancy Forger tell the story about their eNeuro paper that sheds light on the long-standing question of what controls the timing and magnitude of developmental neuronal cell death.